Robert Lustig on what causes insulin resistance
- Insulin resistance is downstream of mitochondrial dysfunction
- "Insulin does everything it can to increase your fat"
- The primary driver of insulin resistance is liver fat. This is what causes the mitochondria to not work.
- 45% of Americans have fatty liver disease. In 1975 no one had it except alcoholics -> "This is the biggest pandemic of all"
- What caused this? Multiple things, but the main one is dietary sugar.
- Other things that cause mitochondrial dysfunction:
- Bad diet generally - not eating the right fats. Omega 3s make mitochondria work better.
- Radiation
- Toxins in the environment, Air pollution.
- There are 7 classes of fats - some will save your life, some will kill you.
- Omega 3s - anti inflammatory
What causes insulin resistance
- Really great explanation of how muscles use glucose, and how insulin resistance
- If you'd asked me before the video, I'd have said that too much carbs was the major danger, but it's actually elevated saturated fat levels in the blood.
How to lose fat
- Insulin - doesn't just partition calories into fat, also shuts off the use of fat for fuel.
Max Lugavere
- "We're overfed & under nourished"
- "Beauty & health are different. "
- "Diseases of civilization"
- "60% of calories from processed foods"
- If you say "Eat until you're full" with processed foods, people will on average eat about 500 calories past what's recommended.
- "Mouthwash is a major problem"
- Nukes nitric oxide which is key in regulating
- Anyone who uses mouthwash twice a day is 2x as likely to develop type 2 diabetes and hypertension.
- "Exercise is as powerful as medicine for regulating blood pressure" Dental
- Floss & brush daily, eat evolutionarily appropriate diet.